mushroom
Lion's Mane
The cognitive mushroom with early clinical evidence for nerve growth, memory and mood support.
Overview
Lion's Mane (Hericium erinaceus) is a medicinal mushroom used in traditional Chinese medicine for centuries. It has attracted significant scientific interest due to its unique compounds — hericenones and erinacines — which appear to stimulate the production of Nerve Growth Factor (NGF), vital for neuron growth and maintenance. While most research has been in animal models or small human trials, results are sufficiently interesting to make this one of the most promising functional mushrooms for cognitive health.
Evidence rating
Animal studies on Lion's Mane are mechanistically compelling. Human trials are limited but show positive signals for mild cognitive impairment, anxiety and depression. The 2009 Mori et al. trial showed significant cognitive improvements in older adults over 16 weeks. More large-scale RCTs are needed.
Common uses
- Early EvidenceSupporting memory and cognitive function
- Early EvidenceNerve growth and neurological support
- Early EvidenceReducing mild anxiety and low mood
- Early EvidenceGut health support
Safety & cautions
Worth checking with a pharmacist if you take medication.
Common forms
Extracts both hericenones and erinacines. The most complete form for cognitive support.
More natural than mycelium products. Ensure standardised for beta-glucan content.
Often contains significant grain filler. Check beta-glucan content before buying.
Food sources
- Fresh Lion's Mane mushroomAvailable in specialist food shops and Asian grocers. Can be pan-fried.